When a "Diabetic Foot Ulcer" is Actually Peripheral Artery Disease

23 Aug 2025

When a "Diabetic Foot Ulcer" is Actually Peripheral Artery Disease When a diabetic foot ulcer is diagnosed, the primary concern is usually the risk of...

When a "Diabetic Foot Ulcer" is Actually Peripheral Artery Disease

When a diabetic foot ulcer is diagnosed, the primary concern is usually the risk of infection and potential amputation. However, in some cases, a foot ulcer may be a symptom of an underlying condition that requires immediate attention – Peripheral Artery Disease (PAD). In this article, we'll explore the link between diabetic foot ulcers and PAD, and discuss how this often-overlooked connection can impact treatment and prognosis.

Peripheral Artery Disease (PAD) is a condition in which the arteries that supply blood to the limbs (arms and legs) become narrowed or blocked, reducing blood flow to the extremities. In diabetic patients, PAD is often a complication of long-standing uncontrolled diabetes, which can lead to atherosclerosis (the buildup of plaque in the arteries) and subsequent reduced blood flow to the legs and feet.

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A diabetic foot ulcer is a common complication of PAD, but not all foot ulcers are PAD-related. However, in patients with a history of diabetes, peripheral neuropathy, and foot ulcers, PAD should always be considered a potential underlying cause.

Recognizing the Signs of PAD

While a diabetic foot ulcer is the most obvious symptom, there are other signs and symptoms that may indicate the presence of PAD. These include:

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  • Pain or cramping in the legs or feet when walking or exercising, which can be a sign of inadequate blood flow to the muscles
  • Poor wound healing in the legs or feet, which can be a sign of reduced blood flow to the affected area
  • Changes in skin color or temperature in the legs or feet, which can be a sign of reduced blood flow
  • Weak or absent pulses in the legs or feet, which can be a sign of PAD

Diagnosing PAD in Diabetic Patients

Diagnosing PAD in diabetic patients typically involves a combination of clinical evaluation, imaging studies, and laboratory tests. These may include:

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  • Ankle-brachial index (ABI): a non-invasive test that measures blood pressure in the ankles and arms to determine blood flow to the legs
  • Segmental Doppler studies: a non-invasive test that uses ultrasound to measure blood flow to specific areas of the legs
  • Arterial imaging studies: such as CT or MRI scans to visualize the arteries and identify blockages or narrowing

Treating PAD in Diabetic Patients

Treatment of PAD in diabetic patients typically involves a combination of lifestyle modifications, medication, and interventional procedures. These may include:

  • Smoking cessation: a critical step in reducing the risk of PAD and its complications
  • Exercise: regular exercise, such as walking, can help improve blood flow to the legs and reduce the risk of PAD
  • Medication: medications such as statins and aspirin can help reduce inflammation and prevent blood clots
  • Interventional procedures: such as angioplasty or stenting may be necessary to restore blood flow to the affected area

Conclusion

In conclusion, a diabetic foot ulcer can be a symptom of Peripheral Artery Disease (PAD), a condition that requires immediate attention. Recognizing the signs and symptoms of PAD, diagnosing the condition, and treating it promptly can help prevent complications and improve outcomes. By working closely with a healthcare provider, diabetic patients can reduce their risk of PAD and its complications, and maintain optimal health.