What to Do During a Severe Hypoglycemia Episode: A Step-by-Step Safety Guide

02 Sep 2025

What to Do During a Severe Hypoglycemia Episode: A Step-by-Step Safety Guide Hypoglycemia, or low blood sugar, is a common concern for individuals wit...

What to Do During a Severe Hypoglycemia Episode: A Step-by-Step Safety Guide

Hypoglycemia, or low blood sugar, is a common concern for individuals with diabetes, especially those who take insulin or certain oral medications. While mild to moderate hypoglycemia can often be managed with quick-acting carbohydrates, severe hypoglycemia can be a frightening and potentially life-threatening situation. Recognizing the signs and knowing the correct steps to take is crucial. This guide provides a step-by-step approach to handling a severe hypoglycemic episode, ensuring safety and minimizing potential harm.

Why Understanding Severe Hypoglycemia is Critical

Severe hypoglycemia occurs when blood sugar levels drop dangerously low, typically below 70 mg/dL (3.9 mmol/L) but can vary. This deprives the brain of the glucose it needs to function correctly, leading to symptoms such as confusion, seizures, loss of consciousness, and, in extreme cases, coma. Individuals with diabetes, their families, and caregivers must be educated about how to recognize and treat severe hypoglycemia.

Here's a quick summary of the importance:

  • Prevention of Complications: Immediate and correct treatment can prevent serious complications like brain damage or death.
  • Reduced Anxiety: Knowing what to do can reduce anxiety for both the person experiencing hypoglycemia and those around them.
  • Empowerment: Proper knowledge empowers individuals to manage their diabetes more effectively.

Recognizing the Signs and Symptoms of Severe Hypoglycemia

The first step in managing severe hypoglycemia is recognizing its symptoms. These can vary from person to person, but common signs include:

Related reading: How To Perform An Accurate Blood Sugar Test At Home Step By Step

  1. Loss of Consciousness: The individual becomes unresponsive and cannot be roused.
  2. Seizures: Uncontrolled shaking or convulsions.
  3. Confusion and Disorientation: The person appears very confused, disoriented, or unable to follow simple instructions.
  4. Inability to Swallow or Cooperate: Difficulty swallowing or an inability to take oral medication or food.
  5. Unusual Behavior: Acting erratically or aggressively without apparent cause.

It is important to note that some individuals may experience hypoglycemia unawareness, where they do not experience the typical warning signs of low blood sugar. This condition increases the risk of severe episodes. Regular monitoring of blood glucose levels and working with a healthcare provider to adjust medication can help mitigate this risk.

| Symptom | Description | | :----------------------------- | :------------------------------------------------------------- | | Loss of Consciousness | Unresponsive and cannot be awakened. | | Seizures | Uncontrolled shaking or convulsions. | | Severe Confusion | Disoriented, unable to follow instructions. | | Inability to Swallow/Cooperate | Cannot take oral medications or food. | | Unusual Behavior | Acting erratically or aggressively. | | Sweating | Profuse sweating, often cold and clammy |

Step-by-Step Guide: What to Do During a Severe Hypoglycemia Episode

When someone is experiencing severe hypoglycemia, prompt action is crucial. Here’s a detailed, step-by-step guide on what to do:

  1. Assess the Situation and Ensure Safety:
    • Check for Responsiveness: Gently try to wake the person by calling their name and lightly shaking their shoulder.
    • Ensure a Safe Environment: Move any objects that could cause harm if the person is having a seizure.
  2. Administer Glucagon Immediately:

    • Locate the Glucagon Kit: If the person with diabetes has a glucagon emergency kit, find it immediately. Glucagon is a hormone that raises blood sugar levels quickly.
    • Prepare the Injection: Follow the instructions on the glucagon kit. Typically, you'll need to mix the glucagon powder with the provided liquid.
    • Administer the Injection: Inject the glucagon into the muscle (usually the thigh, arm, or buttock) as instructed. Do not attempt to give anything by mouth, as the person could choke.
    • Dosage: A typical adult dose is 1 mg. For children, the dose may be lower; check the kit instructions or consult with a healthcare provider in advance.
    • Call for Emergency Medical Assistance:

    • Dial Emergency Services: Immediately call your local emergency number (such as 911 in the United States or 112 in Europe).

      Related reading: A1C Vs Blood Glucose Understanding The Key Differences For Your Diabetes

    • Provide Information: Clearly state that the person is experiencing severe hypoglycemia and is unresponsive or having seizures. Give the dispatcher the exact location and any relevant medical history you know.
    • Follow Instructions: Follow any instructions provided by the emergency dispatcher.
    • Monitor the Person Closely:

    • Stay with the Person: Do not leave the person alone.

    • Observe for Changes: Watch for any changes in their condition, such as improved responsiveness or continued seizures.
    • Turn on Side: If the person is vomiting, turn them on their side to prevent choking.
    • Provide Additional Support After Glucagon Administration:

    • Expect a Delay: Glucagon can take 5-15 minutes to work.

    • Check Blood Sugar: If you have a blood glucose meter, check the person's blood sugar about 15 minutes after administering glucagon.
    • Give Carbohydrates (If Conscious): Once the person regains consciousness and is able to swallow, give them a fast-acting carbohydrate source such as fruit juice, glucose tablets, or regular soda. Follow this with a longer-acting carbohydrate source like crackers or bread.
    • Document the Episode:

    • Record Details: Note the time the episode occurred, the symptoms observed, the dose of glucagon administered, and the person's response.

    • Share with Healthcare Provider: This information will be valuable for the healthcare provider to adjust the person's diabetes management plan.

Here’s a simplified table for quick reference:

| Step | Action | Description | | ---- | ------------------------------------------- | ---------------------------------------------------------------------------------------------------------- | | 1 | Assess and Ensure Safety | Check responsiveness, ensure a safe environment. | | 2 | Administer Glucagon | Locate kit, prepare and inject glucagon (1 mg for adults). | | 3 | Call Emergency Services | Dial emergency number, provide information, and follow instructions. | | 4 | Monitor Closely | Stay with the person, observe changes, and turn on side if vomiting. | | 5 | Provide Carbs (If Conscious) | Check blood sugar after 15 mins, and give fast-acting carbs followed by longer-acting carbs once conscious. | | 6 | Document the Episode | Record details to share with the healthcare provider. |

Understanding Glucagon: The Emergency Treatment for Severe Hypoglycemia

Glucagon is a hormone produced by the pancreas that raises blood glucose levels. In cases of severe hypoglycemia, an injection of glucagon can quickly counteract the effects of low blood sugar. It works by stimulating the liver to release stored glucose into the bloodstream.

Types of Glucagon Kits

There are various types of glucagon kits available, including:

  • Traditional Glucagon Kit: This involves mixing a powdered form of glucagon with a liquid before injecting it.
  • Nasal Glucagon: A more recent option that is administered as a nasal spray, making it easier to use in emergency situations.
  • Premixed Glucagon Pen: A prefilled pen that simplifies the injection process.

How to Administer Glucagon

  1. Traditional Glucagon Kit:

    • Remove the cap from the glucagon vial.
    • Remove the cap from the syringe and insert the needle into the vial.
    • Inject the liquid from the syringe into the glucagon powder.
    • Gently roll the vial between your hands to mix the solution until the glucagon is completely dissolved.
    • Withdraw the glucagon solution back into the syringe.
    • Inject the solution into the person's thigh, arm, or buttock.
  2. Nasal Glucagon:

    • Remove the device from its packaging.
    • Hold the device between your fingers and thumb.
    • Insert the tip of the nozzle into one nostril.
    • Press the plunger firmly to deliver the dose.
  3. Premixed Glucagon Pen:

    • Remove the cap from the pen.
    • Press the pen firmly against the thigh (or other recommended injection site).
    • Press and hold the button to deliver the glucagon.
    • Hold in place for the recommended duration.

Important Considerations When Using Glucagon

  • Expiration Date: Always check the expiration date on the glucagon kit. Expired glucagon may not be effective.
  • Storage: Store the glucagon kit in a cool, dry place, away from direct sunlight.
  • Training: Family members and caregivers should be trained on how to administer glucagon.
  • Side Effects: Common side effects of glucagon include nausea and vomiting.

Prevention Strategies to Avoid Severe Hypoglycemia

Prevention is the best approach to managing severe hypoglycemia. Several strategies can help minimize the risk of episodes:

  1. Regular Blood Glucose Monitoring:

    • Frequency: Regularly check blood glucose levels, especially before meals, after meals, before exercise, and at bedtime.
    • Continuous Glucose Monitors (CGMs): Consider using a CGM, which provides real-time glucose readings and alerts for high and low blood sugar levels.
    • Medication Management:

    • Dosage Adjustments: Work with a healthcare provider to adjust medication dosages as needed based on blood glucose levels, diet, and activity.

    • Timing of Medications: Understand how medications work and take them at the correct times.
    • Meal Planning:

    • Balanced Diet: Follow a balanced meal plan that includes carbohydrates, proteins, and fats.

    • Consistent Timing: Eat meals and snacks at regular intervals to avoid fluctuations in blood sugar levels.
    • Carbohydrate Counting: Learn how to count carbohydrates to match insulin doses appropriately.
    • Related reading: Living With Type 1 Diabetes Tips To Manage Your Blood Glucose Bg

      Exercise Considerations:

    • Monitor Glucose Levels: Check blood glucose levels before, during, and after exercise.

    • Adjust Insulin Doses: Reduce insulin doses or consume extra carbohydrates before exercise, as needed.
    • Carry Snacks: Always carry a fast-acting carbohydrate source during exercise.
    • Education and Awareness:

    • Recognize Symptoms: Be aware of the early signs of hypoglycemia and take prompt action.

    • Educate Family and Friends: Educate family members, friends, and coworkers about diabetes and how to respond to a hypoglycemic episode.
    • Regular check-ups: Regular visit the doctor and diabetes specialist, check your medication, and monitor your condition.
    • Wear Medical identification: Wear a medical ID bracelet or necklace to notify health provider and others of your condition, especially in severe cases.
    • Insulin type: Consider consulting your doctor for using long lasting insulin dose to keep blood glucose in check.
    • Avoid Alcohol: Consult your doctor before taking alcohol, since alcohol consumption can cause hypoglycemia.

| Prevention Strategy | Description | | :------------------------------- | :------------------------------------------------------------------------------------------------------------- | | Regular Glucose Monitoring | Check glucose levels frequently; consider CGM use. | | Medication Management | Adjust dosages as needed; understand medication timing. | | Balanced Diet | Include carbs, proteins, and fats; eat at consistent times; learn carb counting. | | Exercise Precautions | Monitor glucose levels; adjust insulin doses; carry snacks. | | Education and Awareness | Recognize symptoms; educate family and friends. |

The Importance of Education and Preparedness

Education and preparedness are vital for effectively managing severe hypoglycemia. This includes:

  • Diabetes Education Programs: Participate in diabetes education programs to learn about diabetes management, including how to prevent and treat hypoglycemia.
  • Training for Family and Caregivers: Ensure that family members, friends, and caregivers know how to recognize the signs of severe hypoglycemia and how to administer glucagon.
  • Emergency Action Plan: Develop an emergency action plan that outlines the steps to take in case of severe hypoglycemia. Share this plan with family, friends, and caregivers.
  • Regular Review with Healthcare Provider: Regularly review diabetes management plan with a healthcare provider to make necessary adjustments.
  • Stay Informed: Stay up-to-date on the latest research and guidelines for diabetes management.

By following this step-by-step guide and prioritizing education and prevention, individuals with diabetes and their support network can effectively manage severe hypoglycemia and ensure safety.