Severe Hypoglycemia: Emergency Signs and What to Do Next

30 Aug 2025

Severe Hypoglycemia: Emergency Signs and What to Do Next Severe hypoglycemia, or low blood sugar, is a dangerous condition that can arise in individua...

Severe Hypoglycemia: Emergency Signs and What to Do Next

Severe hypoglycemia, or low blood sugar, is a dangerous condition that can arise in individuals with diabetes, particularly those using insulin or certain oral medications. Recognizing the emergency signs and knowing how to respond quickly and effectively is crucial. This article will provide a detailed overview of severe hypoglycemia, including its warning signs, immediate treatment steps, and long-term prevention strategies. It's imperative to treat severe hypoglycemia as a medical emergency, as prolonged episodes can lead to serious complications, including seizures, coma, and even death.

Why Understanding Severe Hypoglycemia is Critical

Understanding the emergency nature of severe hypoglycemia can truly be life-saving. When blood sugar levels drop too low, the brain doesn't get enough glucose, its primary energy source. This can lead to a rapid decline in cognitive and physical function. Effective and immediate action can prevent potentially devastating outcomes.

| Consequence of Severe Hypoglycemia | Potential Outcome | | --------------------------------------- | ---------------------------------------------------------- | | Untreated low blood sugar | Loss of consciousness, seizures, coma | | Delayed treatment | Brain damage, increased risk of accidents and injuries | | Recurrent episodes | Reduced awareness of hypoglycemic symptoms over time |


Recognizing the Emergency Signs of Severe Hypoglycemia

Identifying the signs of severe hypoglycemia is the first and often most critical step in addressing this condition. Individuals may experience a range of symptoms, which can vary in intensity. In many cases, the person experiencing severe hypoglycemia is unable to self-treat due to confusion or unconsciousness.

Primary Signs of Severe Hypoglycemia:

  • Loss of consciousness: This is perhaps the most alarming sign and indicates a critical need for immediate intervention.
  • Seizures: Uncontrolled muscle contractions are a serious indicator that brain function is severely compromised.
  • Inability to eat or drink: Confusion or unresponsiveness prevents the individual from consuming necessary glucose.
  • Erratic or aggressive behavior: Unusual behavior or confusion that isn't typical for the person.
  • Marked confusion or disorientation: Difficulty thinking clearly or knowing where they are.

Subtle Warning Signs that May Precede Severe Hypoglycemia:

Sometimes, subtler symptoms can act as early warnings before the condition escalates. These might include:

  • Severe weakness or fatigue: Feeling extremely tired and unable to perform normal activities.
  • Profuse sweating: Sweating even when not physically active or in a hot environment.
  • Rapid heart rate: A racing heartbeat that feels unusually fast.
  • Blurred or double vision: Difficulty seeing clearly.
  • Numbness or tingling around the mouth: A pins-and-needles sensation, especially around the lips and tongue.
  • Slurred speech: Difficulty speaking clearly, often mistaken for intoxication.

Being aware of these subtle signs can allow for earlier intervention and prevention of a severe episode. It is important for individuals with diabetes, as well as their family members and caregivers, to be thoroughly educated about these symptoms.


Immediate Actions: What to Do When Severe Hypoglycemia Strikes

When someone exhibits signs of severe hypoglycemia, immediate action is necessary. Your response can make a significant difference in preventing serious complications. Here's a step-by-step guide on what to do:

Step 1: Confirm Unresponsiveness and Assess the Situation

  1. Check for responsiveness: Try to rouse the person by gently shaking them and speaking loudly.
  2. Look for medical identification: Check for a medical ID bracelet or necklace that indicates the person has diabetes.
  3. Assess breathing: Ensure the person is breathing adequately.

Step 2: Administer Glucagon (if available)

Glucagon is a hormone that raises blood sugar levels by prompting the liver to release stored glucose into the bloodstream.

  1. Locate the glucagon emergency kit: If the person has diabetes, they may have a glucagon kit prescribed by their doctor. Know where they keep it (e.g., emergency kit, refrigerator).
  2. Prepare the injection: Follow the instructions included with the kit carefully. Usually, this involves mixing a powder with a liquid.
  3. Administer the injection: Inject the glucagon into the thigh, arm, or buttock. The injection can be given through clothing if needed.
  4. Call for emergency medical assistance: Immediately call emergency services (911 in the US) or your local emergency number, even after administering glucagon. This is crucial because glucagon's effects are temporary, and the person needs further medical evaluation.

Step 3: If Glucagon Is Unavailable or You Are Not Trained

If glucagon isn't available, or if you are not trained to administer it:

Related reading: Hyperglycemia 101 A Guide For Persons With Diabetes

Related reading: Decoding Your Blood Sugar Range When To Worry And When To Relax

  1. Call emergency services immediately: Do not delay in calling for professional medical assistance.
  2. Do not attempt to give food or liquids: Because the person is unconscious or unable to swallow safely, attempting to give them anything by mouth could cause choking.

Step 4: Post-Treatment Monitoring

After administering glucagon:

  1. Monitor breathing: Ensure the person continues to breathe normally. If breathing stops, begin CPR if you are trained to do so.
  2. Turn the person on their side: Once they regain consciousness, help them turn onto their side to prevent choking in case of vomiting.
  3. Check blood sugar: If you have access to a glucose meter, check their blood sugar levels.
  4. Give a fast-acting carbohydrate: Once the person is fully awake and able to swallow, give them a source of fast-acting carbohydrates like juice, glucose tablets, or regular (non-diet) soda. This will help stabilize their blood sugar levels.
  5. Follow up with a longer-acting carbohydrate: After the fast-acting carbs, provide a more substantial snack like crackers with peanut butter or a piece of whole-wheat bread to help prevent another drop in blood sugar.

Important Note: Always inform the paramedics or healthcare providers about the glucagon injection, including the time it was administered and the dose.


Understanding the Causes of Severe Hypoglycemia

Knowing what can lead to severe hypoglycemia is essential for prevention. Several factors can contribute to a dangerous drop in blood sugar levels in individuals with diabetes.

Common Causes of Severe Hypoglycemia:

  • Excessive insulin dosage: Taking too much insulin can overwhelm the body's glucose balance.
    • Example: Accidentally administering a double dose or not adjusting insulin levels properly after changes in diet or exercise.
  • Skipping meals or inadequate carbohydrate intake: Insufficient food intake, especially carbohydrates, can result in low blood sugar.
    • Example: Skipping lunch or dinner or not eating enough carbs to match insulin doses.
  • Increased physical activity without adjusting medication or food intake: Exercise increases glucose utilization, potentially leading to hypoglycemia if medications and food are not adjusted.
    • Example: Engaging in strenuous exercise without reducing insulin or consuming additional carbohydrates.
  • Alcohol consumption: Alcohol can interfere with the liver's ability to release glucose, especially when consumed without food.
    • Example: Drinking alcohol on an empty stomach or consuming too much alcohol can lead to a dangerous drop in blood sugar.
  • Kidney or liver problems: Impaired kidney or liver function can affect the metabolism of insulin and glucose.
    • Example: Conditions such as renal failure or cirrhosis can disrupt the normal regulation of blood sugar.
  • Certain medications: Some medications, such as sulfonylureas, can stimulate insulin release and increase the risk of hypoglycemia.
    • Example: Combining sulfonylureas with other medications that lower blood sugar can amplify their effects.
  • Illness or infection: During illness, appetite may decrease, and the body's response to insulin can change.
    • Example: Vomiting or diarrhea can make it difficult to maintain consistent carbohydrate intake, increasing the risk of hypoglycemia.

Less Common Causes:

  • Insulinoma: A rare tumor of the pancreas that produces excess insulin.
  • Non-diabetic hypoglycemia: Hypoglycemia occurring in individuals without diabetes, often due to specific medical conditions or medications.

Specific Scenarios:

| Scenario | Specific Cause | Prevention Strategy | | --------------------------------------------- | ------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------- | | Intense workout session | Failure to reduce insulin or increase carbohydrate intake prior to or during exercise. | Monitor blood glucose before, during, and after exercise; adjust insulin doses or carbohydrate intake as needed. | | Accidental overdose of insulin | Human error in administering insulin. | Use insulin pens with clear dosing increments; double-check doses with a second person; consider using a continuous glucose monitor (CGM). | | Post-meal hypoglycemia after gastric bypass | Rapid absorption of carbohydrates leading to an overproduction of insulin. | Eat smaller, more frequent meals; limit high-sugar foods; consider consulting with a dietitian experienced in post-bariatric nutrition. |


Long-Term Prevention Strategies for Severe Hypoglycemia

Preventing severe hypoglycemia involves a proactive approach focused on managing blood sugar levels, educating individuals and their caregivers, and using technology to improve glucose control.

Related reading: Living Well With Type 1 Diabetes Mastering Daily Blood Glucose Bg Control

Key Prevention Strategies:

  1. Regular Blood Glucose Monitoring:
    • Importance: Consistent monitoring is the cornerstone of diabetes management. It provides real-time data on blood glucose levels, allowing for timely adjustments in medication, diet, and activity.
    • Recommendations: Check blood glucose levels before meals, two hours after meals, before bedtime, and before, during, and after exercise. People using insulin may need to check more frequently.
  2. Careful Insulin and Medication Management:
    • Importance: Accurate dosing and timing of insulin and oral medications are crucial for preventing hypoglycemia.
    • Recommendations: Work closely with your healthcare provider to establish an appropriate medication regimen. Understand the onset, peak, and duration of your insulin. Always double-check insulin doses before administering.
  3. Consistent Meal Timing and Carbohydrate Intake:
    • Importance: Regular meal times and consistent carbohydrate intake help stabilize blood glucose levels.
    • Recommendations: Eat meals and snacks at consistent times each day. Understand carbohydrate counting and adjust insulin doses accordingly. Avoid skipping meals.
  4. Adjusting Insulin and Medications for Exercise:
    • Importance: Exercise increases glucose utilization, so adjustments in insulin or carbohydrate intake are often necessary.
    • Recommendations: Monitor blood glucose before, during, and after exercise. Reduce insulin doses or consume additional carbohydrates as needed.
  5. Limiting Alcohol Consumption:
    • Importance: Alcohol can interfere with glucose regulation, especially when consumed without food.
    • Recommendations: If you choose to drink alcohol, do so in moderation and always with food. Monitor blood glucose levels carefully.
  6. Wearing a Medical Identification:
    • Importance: A medical ID bracelet or necklace can alert others to your diabetes in case of an emergency.
    • Recommendations: Wear a medical ID at all times with information about your diabetes and any medications you are taking.
  7. Educating Family, Friends, and Caregivers:
    • Importance: Educated individuals can recognize the signs of hypoglycemia and administer glucagon if necessary.
    • Recommendations: Teach family members, friends, and caregivers about the signs of hypoglycemia and how to administer glucagon. Keep a glucagon kit readily available.
  8. Continuous Glucose Monitoring (CGM):
    • Importance: CGMs provide continuous, real-time glucose readings and can alert users to impending hypoglycemia.
    • Recommendations: Consider using a CGM system to monitor glucose trends and receive alerts for low blood sugar. Many CGMs can communicate with insulin pumps to automatically adjust insulin delivery.
  9. Insulin Pump Therapy:
    • Importance: Insulin pumps can deliver insulin more precisely than injections, reducing the risk of hypoglycemia.
    • Recommendations: If you are on insulin, discuss the possibility of insulin pump therapy with your healthcare provider.
  10. Regular Medical Checkups:
    • Importance: Routine medical checkups can identify and address any underlying health issues that may contribute to hypoglycemia.
    • Recommendations: See your healthcare provider regularly for comprehensive diabetes management, including assessment of kidney and liver function.

Tools and Technologies:

| Tool/Technology | Benefit | How It Helps Prevent Hypoglycemia | | -------------------------------- | ------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------------- | | Continuous Glucose Monitor (CGM) | Provides real-time glucose readings and alerts for impending hypoglycemia. | Alerts the user to take corrective action before glucose levels drop too low; can communicate with insulin pumps. | | Insulin Pump | Delivers insulin precisely and can be programmed to adjust insulin delivery based on glucose trends. | Allows for more precise insulin delivery, reducing the risk of both hyperglycemia and hypoglycemia. | | Smart Insulin Pens | Tracks insulin doses and provides reminders to help prevent missed doses or accidental overdoses. | Ensures accurate insulin dosing, reducing the likelihood of errors that can lead to hypoglycemia. | | Mobile Apps | Tracks glucose levels, food intake, and exercise, and provides personalized recommendations for diabetes management. | Helps users make informed decisions about medication, diet, and exercise to maintain stable glucose levels. |

By implementing these comprehensive strategies, individuals with diabetes can significantly reduce their risk of experiencing severe hypoglycemia and improve their overall quality of life.