Severe Hypoglycemia: A Step-by-Step Emergency Action Plan

02 Sep 2025

Severe Hypoglycemia: A Step-by-Step Emergency Action Plan Severe hypoglycemia, or extremely low blood sugar, is a critical medical condition that can ...

Severe Hypoglycemia: A Step-by-Step Emergency Action Plan

Severe hypoglycemia, or extremely low blood sugar, is a critical medical condition that can occur in people with diabetes, particularly those using insulin or certain oral medications. It's characterized by a blood glucose level that is so low that the individual is unable to treat themselves and requires assistance from another person. Recognizing and acting quickly is vital to prevent serious complications like seizures, loss of consciousness, brain damage, or even death. This article provides a comprehensive, step-by-step emergency action plan to help you respond effectively to severe hypoglycemia.

Understanding Severe Hypoglycemia

Hypoglycemia occurs when the blood glucose level drops below 70 mg/dL (3.9 mmol/L). Severe hypoglycemia is a stage where blood glucose levels are critically low, impairing brain function and requiring external assistance. Common causes include:

  • Excessive insulin: Taking too much insulin relative to food intake or activity level.
  • Skipped or delayed meals: Not eating enough carbohydrates or missing meals altogether.
  • Increased physical activity: Exercising more intensely or for a longer duration than usual without adjusting medication or carbohydrate intake.
  • Alcohol consumption: Alcohol can interfere with the liver's ability to release glucose into the bloodstream.
  • Certain medications: Some oral diabetes medications, especially sulfonylureas, can cause hypoglycemia.
  • Kidney or liver problems: Impaired organ function can affect glucose metabolism and medication clearance.

Recognizing the Symptoms

Recognizing the symptoms of severe hypoglycemia is crucial for timely intervention. While symptoms can vary from person to person, common signs include:

  • Confusion or disorientation: Difficulty thinking clearly or understanding instructions.
  • Loss of coordination: Unsteadiness, stumbling, or difficulty with motor skills.
  • Slurred speech: Difficulty speaking clearly.
  • Seizures: Uncontrolled muscle contractions and loss of consciousness.
  • Loss of consciousness: Unresponsiveness to stimuli.
  • Profuse sweating: Excessive perspiration, often described as "cold sweats."
  • Rapid heart rate: Palpitations or a racing pulse.
  • Weakness or fatigue: Feeling unusually tired or drained.
  • Visual disturbances: Blurred vision or double vision.

Step-by-Step Emergency Action Plan for Severe Hypoglycemia

This action plan outlines the essential steps to take when someone is experiencing severe hypoglycemia. Remember, time is of the essence.

Step 1: Assess the Situation and Ensure Safety

  1. Check for Responsiveness: Gently shake the person and ask if they are okay. If there is no response, they are likely experiencing severe hypoglycemia.
  2. Ensure a Safe Environment: Move the person to a safe location, away from potential hazards like traffic or sharp objects.
  3. Look for Medical Identification: Check for a medical bracelet, necklace, or card that identifies them as having diabetes and provides emergency contact information.

Step 2: Administer Glucagon

Glucagon is a hormone that raises blood glucose levels by stimulating the liver to release stored glucose. It is the primary treatment for severe hypoglycemia in individuals who are unable to take glucose orally.

  1. Locate the Glucagon Kit: If the person has diabetes, they should have a glucagon emergency kit readily available. If not, call emergency services immediately.
  2. Prepare the Glucagon Injection:
    • Follow the kit instructions carefully. Glucagon kits typically include a syringe containing sterile water or saline and a vial containing powdered glucagon.
    • Inject the fluid from the syringe into the vial.
    • Gently roll the vial to mix the solution until the glucagon is completely dissolved. Do not shake vigorously, as this can create air bubbles.
    • Withdraw the reconstituted glucagon solution back into the syringe.
  3. Administer the Glucagon Injection:
    • Choose an injection site: Recommended sites include the upper arm, thigh, or buttock.
    • Clean the injection site with an alcohol swab, if available.
    • Insert the needle at a 90-degree angle into the muscle.
    • Inject the entire contents of the syringe.
    • Withdraw the needle and apply gentle pressure to the injection site with a clean cotton ball or gauze pad.
  4. Dosage:
    • Adults and children weighing more than 25 kg (55 lbs): Administer the full 1 mg dose of glucagon.
    • Children weighing less than 25 kg (55 lbs): Administer half of the 1 mg dose (0.5 mg). Some kits may have pre-measured doses for children.

Example:

| Patient Weight | Glucagon Dosage | |-------------------------|---------------------| | Over 25 kg (55 lbs) | 1 mg | | Under 25 kg (55 lbs) | 0.5 mg |

Step 3: Call for Emergency Medical Assistance

  1. Call Emergency Services (911 in the US, 112 in Europe, 000 in Australia): Explain that the person is experiencing severe hypoglycemia and has received a glucagon injection. Provide the person's location and any relevant medical history if known.
  2. Stay on the Line: Follow the dispatcher's instructions and answer any questions they may have.

Step 4: Monitor the Person

  1. Observe for Improvement: Glucagon typically takes 10-15 minutes to raise blood glucose levels. Monitor the person closely for signs of improvement, such as increased alertness, responsiveness, and coordination.
  2. Check Blood Glucose: If a glucose meter is available and you are trained to use it, check the person's blood glucose level 15 minutes after administering glucagon.
  3. If No Improvement After 15 Minutes: If there is no improvement after 15 minutes, and emergency services have not yet arrived, consider administering a second dose of glucagon if another kit is available and you are comfortable doing so.
  4. Prepare for Vomiting: Glucagon can sometimes cause nausea and vomiting. Turn the person on their side to prevent choking if vomiting occurs.

Step 5: Provide Oral Glucose Once Conscious

Important: Do not give anything by mouth to an unconscious person due to the risk of choking.

  1. Once the person regains consciousness and is able to swallow safely: Offer them a fast-acting source of glucose, such as:
    • Glucose tablets: Follow the package instructions for the appropriate dosage.
    • Fruit juice: 4-6 ounces (120-180 ml)
    • Regular soda (not diet): 4-6 ounces (120-180 ml)
    • Honey or syrup: 1 tablespoon
  2. Follow with a Longer-Acting Carbohydrate: After the initial glucose boost, provide a longer-acting carbohydrate source, such as:
    • Crackers with peanut butter
    • A sandwich
    • A piece of fruit
  3. Monitor Blood Glucose Regularly: Check blood glucose levels every 1-2 hours to ensure they remain within a safe range.

Preventive Measures to Avoid Severe Hypoglycemia

Prevention is key to avoiding severe hypoglycemia. People with diabetes can take several steps to minimize their risk:

  1. Regular Blood Glucose Monitoring: Check blood glucose levels frequently, especially before meals, before and after exercise, and at bedtime.
  2. Medication Management: Work closely with a healthcare provider to adjust medication dosages as needed, particularly insulin. Understand the peak action times of your medications.
  3. Meal Planning: Eat regular meals and snacks, and ensure they contain adequate carbohydrates.
  4. Exercise Planning: Adjust medication dosages or carbohydrate intake before, during, and after exercise. Monitor blood glucose levels more frequently during and after physical activity.
  5. Alcohol Consumption: Consume alcohol in moderation and always with food. Monitor blood glucose levels closely when drinking alcohol.
  6. Education: Educate family members, friends, and coworkers about the signs and symptoms of hypoglycemia and how to administer glucagon.
  7. Medical Identification: Wear a medical bracelet or necklace that identifies you as having diabetes and provides emergency contact information.
  8. Carry Fast-Acting Glucose: Always carry a source of fast-acting glucose, such as glucose tablets or gel, to treat mild hypoglycemia promptly.
  9. Glucagon Awareness: Ensure that glucagon kits are not expired and are easily accessible in both your home and when traveling. Train family and close friends how to administer glucagon effectively.

Table: Strategies to Prevent Hypoglycemia

| Strategy | Description | |------------------------|--------------------------------------------------------------------------------| | Blood Glucose Monitoring | Regularly check levels, especially before and after meals/exercise. | | Medication Adjustment | Adjust dosages under professional guidance. | | Consistent Meal Timing | Eat regular meals and snacks to maintain steady glucose levels. | | Alcohol Moderation | Consume alcohol with food and monitor levels closely. | | Exercise Precautions | Adjust medication/food intake; monitor during/after physical activity. | | Educate Others | Inform those around you about hypoglycemia and emergency procedures. |


Important Considerations and Legal Aspects

When to Administer Glucagon

Related reading: What Is A Normal Blood Sugar Level For Persons With Diabetes

Glucagon should only be administered when the person is unable to take glucose orally, typically because they are unconscious, having a seizure, or too confused to swallow safely. Administering glucagon unnecessarily can lead to a rebound high blood glucose level (hyperglycemia).

Legal Protection for Good Samaritans

In many jurisdictions, "Good Samaritan" laws provide legal protection to individuals who provide emergency assistance in good faith. These laws typically protect individuals from liability for unintentional harm caused while attempting to help someone in distress. Familiarize yourself with the Good Samaritan laws in your area.

Glucagon Availability and Cost

Glucagon is available by prescription in most countries. The cost of glucagon kits can vary depending on the brand and insurance coverage. There are several different types of glucagon formulations available, including traditional injectable kits, nasal sprays, and pre-filled syringes. Discuss the best option for you with your healthcare provider.

Review and Practice

Regularly review this emergency action plan and practice the steps, including how to prepare and administer glucagon. Consider using a training kit or dummy injector to familiarize yourself with the process. Encourage family members and caregivers to participate in training sessions.

Hypoglycemia Unawareness

Related reading: A1C Vs Daily Blood Sugar Test Which Is More Important For Control

Some people with diabetes may develop "hypoglycemia unawareness," meaning they no longer experience the warning signs of low blood sugar. This increases their risk of severe hypoglycemia. Regular blood glucose monitoring and working closely with a healthcare provider are particularly important for individuals with hypoglycemia unawareness. Continuous Glucose Monitoring (CGM) devices can also be valuable in detecting and preventing hypoglycemia.

Related reading: The Diabetic Diet Plan That Can Help Stabilize Your Blood Sugar

Special Considerations for Children

The glucagon dosage for children is typically lower than for adults and is based on body weight. Always follow the instructions provided with the glucagon kit and consult with a healthcare provider for specific guidance.

Documenting the Event

After administering glucagon and calling for emergency medical assistance, document the event as thoroughly as possible. Include the time of the incident, the symptoms observed, the glucagon dosage administered, and the response to treatment. This information can be helpful for healthcare providers in determining the underlying cause of the hypoglycemia and adjusting the person's diabetes management plan.


Additional Resources and Support

  • American Diabetes Association (ADA): Provides comprehensive information on diabetes management, including hypoglycemia.
  • Juvenile Diabetes Research Foundation (JDRF): Focuses on research and advocacy for type 1 diabetes.
  • Local Diabetes Education Centers: Offer classes and support groups for people with diabetes and their families.
  • Healthcare Provider: Consult with your doctor or diabetes educator for personalized advice and support.

Table: Useful Resources for Diabetes Management

| Resource | Description | |---------------------------------|-----------------------------------------------------------------------------------------------------------------| | American Diabetes Association | Offers comprehensive information and resources on diabetes management, including hypoglycemia awareness. | | Juvenile Diabetes Research Foundation | Dedicated to research and support for individuals and families affected by type 1 diabetes. | | Local Diabetes Centers | Provide education, support groups, and individual counseling to help manage diabetes effectively. | | Your Healthcare Provider | Offers personalized guidance on managing your diabetes, adjusting medications, and handling emergencies. |

In conclusion, knowing how to respond to severe hypoglycemia is essential for anyone who interacts with individuals who have diabetes. By following this step-by-step emergency action plan and taking preventive measures, you can help ensure the safety and well-being of those at risk. Being prepared, informed, and proactive can make a life-saving difference. Always consult with a healthcare professional for personalized guidance on managing diabetes and hypoglycemia.