Low Blood Sugar (Hypoglycemia): Causes, Symptoms, and Treatment

23 Aug 2025

Low Blood Sugar (Hypoglycemia): Causes, Symptoms, and Treatment Low blood sugar, also known as hypoglycemia, is a condition that occurs when the level...

Low Blood Sugar (Hypoglycemia): Causes, Symptoms, and Treatment

Low blood sugar, also known as hypoglycemia, is a condition that occurs when the level of glucose (sugar) in your blood drops below normal. Glucose is your body's main source of energy, so when your blood sugar levels are too low, you may experience a variety of symptoms, ranging from mild to severe. Understanding the causes of hypoglycemia, recognizing its symptoms, and knowing how to treat it are essential for managing this condition effectively.

What is Hypoglycemia?

Hypoglycemia is generally defined as a blood glucose level below 70 mg/dL (3.9 mmol/L). While this number can vary slightly depending on individual circumstances, it serves as a general guideline for identifying when blood sugar is dangerously low. It's crucial to understand that hypoglycemia is not a disease in itself but rather a condition that can result from various underlying issues, most commonly related to diabetes management.

Causes of Hypoglycemia

The causes of hypoglycemia are varied and depend on whether or not a person has diabetes.

Hypoglycemia in People with Diabetes

For individuals with diabetes, especially those who take insulin or certain oral medications, the most common cause of hypoglycemia is related to diabetes management:

Related reading: The Ultimate Guide To Blood Sugar Friendly Meals For All Day Energy

  • Excess Insulin: Taking too much insulin relative to food intake is a primary trigger. This can occur due to miscalculated dosages or accidental overdoses.
  • Skipping Meals or Delaying Meals: Inconsistent meal schedules or skipping meals, particularly when taking insulin or diabetes medications, can lead to a drop in blood sugar levels.
  • Intense Exercise: Physical activity increases glucose uptake by muscles. If you don’t adjust your insulin or consume extra carbohydrates before or during exercise, your blood sugar may drop too low.
  • Alcohol Consumption: Alcohol can interfere with the liver's ability to release glucose into the bloodstream, especially when consumed on an empty stomach.
  • Certain Diabetes Medications: Some oral diabetes medications, particularly sulfonylureas, stimulate the pancreas to produce more insulin. If this effect is not balanced with food intake, hypoglycemia can result.

Hypoglycemia in People Without Diabetes (Non-Diabetic Hypoglycemia)

Hypoglycemia is less common in people without diabetes, but it can still occur due to several factors:

  • Reactive Hypoglycemia: This type occurs within a few hours after eating a meal, typically one high in carbohydrates. The body releases too much insulin in response to the meal, leading to a rapid drop in blood sugar.
  • Fasting Hypoglycemia: This type can be caused by various underlying conditions, including:
    • Medications: Certain medications (not related to diabetes) can sometimes cause hypoglycemia as a side effect.
    • Excessive Alcohol Consumption: As mentioned earlier, alcohol can interfere with glucose production by the liver.
    • Severe Liver Disease: A compromised liver may not be able to store and release glucose effectively.
    • Kidney Failure: Kidney problems can affect glucose metabolism.
    • Tumors: Rarely, tumors can produce insulin-like substances, leading to hypoglycemia.
    • Hormonal Deficiencies: Deficiencies in certain hormones, such as cortisol or growth hormone, can impact blood sugar regulation.
  • Post-Gastric Bypass Surgery: After gastric bypass surgery, rapid emptying of the stomach and absorption of glucose can trigger reactive hypoglycemia.
  • Hereditary Metabolic Disorders: Some rare genetic conditions can impact glucose metabolism.

Symptoms of Hypoglycemia

Recognizing the symptoms of hypoglycemia is crucial for prompt treatment. Symptoms can vary in severity and may differ from person to person.

Mild to Moderate Symptoms

  • Shakiness
  • Sweating
  • Dizziness or lightheadedness
  • Hunger
  • Irritability or anxiety
  • Confusion
  • Rapid heartbeat (palpitations)
  • Blurred vision
  • Headache
  • Weakness or fatigue

Severe Symptoms

If low blood sugar is not treated promptly, it can progress to more severe symptoms:

  • Difficulty concentrating or thinking clearly
  • Slurred speech
  • Seizures
  • Loss of consciousness
  • Coma

It is crucial to treat severe hypoglycemia immediately to prevent serious complications.

Diagnosing Hypoglycemia

If you suspect you have hypoglycemia, especially if you have diabetes, it is essential to check your blood sugar level with a blood glucose meter. If your blood sugar is below 70 mg/dL, you should take steps to raise it.

For people without diabetes who experience symptoms of hypoglycemia, a healthcare provider may perform additional tests to determine the underlying cause. These tests can include:

  • Fasting blood glucose test: Measures blood sugar after fasting for a specific period.
  • Mixed-meal tolerance test: Measures blood sugar and insulin levels after consuming a mixed meal.
  • Medical history and physical examination: Helps identify potential contributing factors.

Treatment of Hypoglycemia

The treatment of hypoglycemia depends on the severity of the condition and whether the person has diabetes.

Related reading: The Prediabetes Diet 15 Foods That Help Control Blood Sugar

Immediate Treatment for Low Blood Sugar (15/15 Rule)

The 15/15 rule is a commonly recommended approach for treating mild to moderate hypoglycemia:

  1. Check your blood sugar: Confirm that your blood sugar is below 70 mg/dL.
  2. Consume 15 grams of fast-acting carbohydrates: Examples include:
    • 3-4 glucose tablets
    • 1/2 cup (4 ounces) of juice (not sugar-free)
    • 1/2 can (6 ounces) of regular soda (not sugar-free)
    • 1 tablespoon of honey or sugar
  3. Wait 15 minutes: Allow time for your blood sugar to rise.
  4. Recheck your blood sugar: If it is still below 70 mg/dL, repeat the process.
  5. Eat a meal or snack: Once your blood sugar is back within a normal range, eat a meal or snack containing protein and complex carbohydrates to stabilize it and prevent another drop.

Treatment for Severe Hypoglycemia

Severe hypoglycemia requires immediate intervention. If someone is unconscious or unable to swallow:

  • Administer Glucagon: Glucagon is a hormone that stimulates the liver to release stored glucose into the bloodstream. People with diabetes who are at risk of severe hypoglycemia should have a glucagon emergency kit and family members or caregivers should be trained on how to administer it. Glucagon can be administered via injection or nasal spray.
  • Call Emergency Services: After administering glucagon, call 911 (or your local emergency number) to ensure the person receives proper medical attention.

Long-Term Management of Hypoglycemia

The long-term management of hypoglycemia involves addressing the underlying cause and making lifestyle adjustments:

  • For people with diabetes:
    • Work with a healthcare provider: Adjust insulin dosages or medication regimens as needed.
    • Monitor blood sugar levels regularly: This helps identify patterns and prevent future episodes of hypoglycemia.
    • Eat consistent meals and snacks: Avoid skipping meals and maintain a regular eating schedule.
    • Adjust insulin for exercise: Consult with your doctor or diabetes educator about how to adjust insulin or consume extra carbohydrates before, during, and after physical activity.
    • Avoid excessive alcohol consumption: If you choose to drink alcohol, do so in moderation and with food.
  • For people without diabetes:
    • Identify and treat the underlying cause: This may involve addressing dietary issues, managing medications, or treating underlying medical conditions.
    • Eat balanced meals: Focus on complex carbohydrates, protein, and healthy fats to stabilize blood sugar levels.
    • Avoid sugary drinks and refined carbohydrates: These can cause rapid spikes and drops in blood sugar.
    • Eat frequent, small meals: This can help prevent reactive hypoglycemia.

Preventing Hypoglycemia

Prevention is crucial for minimizing the risk of hypoglycemia. Here are some strategies:

  • Regular Blood Sugar Monitoring: If you have diabetes, regular blood sugar monitoring is essential.
  • Consistent Meal Timing: Avoid skipping meals and try to eat at consistent times each day.
  • Education and Awareness: Understand the signs and symptoms of hypoglycemia and how to treat it promptly.
  • Medical Identification: Wear a medical ID bracelet or necklace indicating that you have diabetes and/or are prone to hypoglycemia.
  • Emergency Preparedness: Carry a source of fast-acting carbohydrates with you at all times. Ensure that family members and caregivers know how to recognize and treat hypoglycemia, including how to administer glucagon.

Hypoglycemia and Other Health Conditions

Hypoglycemia can sometimes be associated with other health conditions, which makes accurate diagnosis and management even more important. Conditions that may impact or be impacted by hypoglycemia include:

Related reading: Blood Sugar Mg Dl Vs Mmol L Understanding Your Test Results

  • Diabetes Insipidus: Though the names are similar, diabetes insipidus is a separate condition that involves problems with fluid balance and has no direct connection to blood sugar levels.
  • Adrenal Insufficiency: A condition where the adrenal glands don't produce enough cortisol, which can impact blood sugar regulation.
  • Eating Disorders: Conditions like anorexia and bulimia can significantly disrupt blood sugar levels and lead to hypoglycemia.

Conclusion

Hypoglycemia, or low blood sugar, is a condition that can affect both individuals with and without diabetes. Recognizing the causes of hypoglycemia, understanding its symptoms, and knowing how to treat it are vital for maintaining your health and preventing potentially serious complications. If you experience frequent episodes of hypoglycemia, consult with a healthcare provider to determine the underlying cause and develop an appropriate management plan. Proper monitoring, lifestyle adjustments, and prompt treatment can help you effectively manage hypoglycemia and maintain stable blood sugar levels.


Note: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for any health concerns or before making any decisions related to your health or treatment.