Hyperglycemia vs. Hypoglycemia: Know the Warning Signs

02 Sep 2025

Hyperglycemia vs. Hypoglycemia: Know the Warning Signs Understanding the difference between hyperglycemia and hypoglycemia is crucial for anyone manag...

Hyperglycemia vs. Hypoglycemia: Know the Warning Signs

Understanding the difference between hyperglycemia and hypoglycemia is crucial for anyone managing diabetes or at risk of developing it. These two conditions represent opposite extremes in blood sugar levels – hyperglycemia means high blood sugar, while hypoglycemia means low blood sugar. Recognizing the warning signs and knowing how to respond can significantly impact your health and well-being. This article provides a comprehensive guide to differentiating between these conditions, identifying their symptoms, and taking appropriate action.

Understanding Hyperglycemia (High Blood Sugar)

Hyperglycemia occurs when there is too much glucose in the blood. This can happen if your body doesn't produce enough insulin, if your cells are resistant to insulin (insulin resistance), or if you consume more carbohydrates than your body can process. Over time, chronic hyperglycemia can lead to serious health complications affecting the heart, kidneys, eyes, and nerves.

Related reading: Continuous Glucose Monitor Cgm Vs Finger Prick Which Is Better

Common Causes of Hyperglycemia:

  • Missed or insufficient insulin doses: This is common in individuals with type 1 diabetes.
  • Insulin resistance: Often seen in type 2 diabetes, where cells don't respond effectively to insulin.
  • Overeating or consuming high-carbohydrate foods: The body may not be able to process the excess glucose quickly enough.
  • Inactivity: Lack of physical activity can reduce insulin sensitivity.
  • Stress or illness: These can cause hormonal changes that raise blood sugar levels.
  • Certain medications: Some medications, such as steroids, can increase blood sugar levels.

Warning Signs of Hyperglycemia:

The symptoms of hyperglycemia can develop slowly over several days or weeks. This makes it easy to overlook them until blood sugar levels become significantly elevated. Here's what to watch out for:

  • Frequent urination: High blood sugar causes the kidneys to try and filter out excess glucose, leading to increased urination.
  • Increased thirst: As the body loses fluids through frequent urination, you become dehydrated and feel excessively thirsty.
  • Blurred vision: High blood sugar can affect the lens of the eye, causing temporary blurred vision.
  • Fatigue: The body's cells are not getting enough energy, leading to feelings of tiredness and weakness.
  • Headache: Elevated blood sugar levels can cause headaches.
  • Slow-healing cuts or sores: High blood sugar can impair the body's ability to heal.
  • Dry, itchy skin: Dehydration and poor circulation can contribute to dry and itchy skin.
  • Unexplained weight loss: In severe cases, the body may start breaking down muscle for energy.
  • Frequent infections: High blood sugar can weaken the immune system, making you more susceptible to infections.

Diagnosing Hyperglycemia:

Hyperglycemia is typically diagnosed through blood glucose testing. Common tests include:

  • Fasting plasma glucose (FPG) test: Measures blood sugar after an overnight fast (at least 8 hours). A reading of 126 mg/dL or higher on two separate tests indicates diabetes.
  • Random plasma glucose test: Measures blood sugar at any time of day without regard to meals. A reading of 200 mg/dL or higher, along with symptoms of diabetes, can indicate diabetes.
  • A1C test: Measures average blood sugar levels over the past 2-3 months. An A1C of 6.5% or higher indicates diabetes.
  • Oral glucose tolerance test (OGTT): Measures blood sugar levels before and after drinking a sugary liquid. A reading of 200 mg/dL or higher two hours after drinking the liquid indicates diabetes.

| Test | Normal Range | Prediabetes Range | Diabetes Range | | :-------------------------- | :----------------------------- | :------------------------- | :----------------------------- | | Fasting Plasma Glucose | Less than 100 mg/dL | 100-125 mg/dL | 126 mg/dL or higher | | A1C | Less than 5.7% | 5.7-6.4% | 6.5% or higher | | Oral Glucose Tolerance Test | Less than 140 mg/dL (2 hours) | 140-199 mg/dL (2 hours) | 200 mg/dL or higher (2 hours) |

Managing Hyperglycemia:

Managing hyperglycemia involves a combination of lifestyle changes, medication, and regular monitoring.

  • Diet: Following a balanced diet that is low in carbohydrates and rich in fiber, fruits, and vegetables can help stabilize blood sugar levels. Portion control is also important.
  • Exercise: Regular physical activity increases insulin sensitivity and helps the body use glucose for energy. Aim for at least 150 minutes of moderate-intensity exercise per week.
  • Medication: People with type 1 diabetes will require insulin. Those with type 2 diabetes might also require it. Medications like metformin work to improve insulin sensitivity and reduce glucose production by the liver.
  • Monitoring: Regularly check blood sugar levels using a glucose meter and keep a log of your readings. This will help you and your doctor track your progress and make adjustments to your treatment plan as needed.
  • Hydration: Staying well-hydrated helps the kidneys flush out excess glucose.

Understanding Hypoglycemia (Low Blood Sugar)

Hypoglycemia, also known as low blood sugar, occurs when the level of glucose in the blood drops too low to fuel the body's cells properly. This is typically defined as a blood sugar level below 70 mg/dL. Hypoglycemia is more common in people with diabetes, especially those who take insulin or certain oral medications that stimulate insulin release.

Common Causes of Hypoglycemia:

  • Taking too much insulin or diabetes medication: Overmedication can lead to a rapid drop in blood sugar.
  • Skipping meals or eating too little: Insufficient carbohydrate intake can cause blood sugar to plummet.
  • Exercising more than usual: Physical activity uses up glucose, so increased exercise without adjusting medication or food intake can lead to hypoglycemia.
  • Drinking alcohol, especially on an empty stomach: Alcohol can interfere with the liver's ability to release glucose into the bloodstream.
  • Kidney or liver problems: These organs play a role in regulating blood sugar, so problems with them can lead to hypoglycemia.
  • Certain medical conditions: Some conditions, such as tumors that produce excess insulin (insulinomas), can cause hypoglycemia.

Warning Signs of Hypoglycemia:

The symptoms of hypoglycemia can come on suddenly and can range from mild to severe. It’s important to recognize the signs early to prevent serious complications.

  • Shakiness: Low blood sugar can trigger the release of adrenaline, causing tremors and shakiness.
  • Sweating: Adrenaline release can also cause excessive sweating.
  • Dizziness or lightheadedness: Low blood sugar can impair brain function, leading to dizziness and lightheadedness.
  • Rapid heartbeat: The heart may beat faster as the body tries to compensate for the lack of glucose.
  • Anxiety or nervousness: Hypoglycemia can cause feelings of anxiety, irritability, or nervousness.
  • Hunger: The body signals that it needs more glucose by triggering hunger.
  • Blurred vision: Similar to hyperglycemia, low blood sugar can affect vision.
  • Weakness or fatigue: The body lacks sufficient energy to function properly.
  • Headache: Low blood sugar can also cause headaches.
  • Confusion or difficulty concentrating: The brain needs glucose to function, so low blood sugar can impair cognitive function.
  • Seizures or loss of consciousness: In severe cases, hypoglycemia can lead to seizures or loss of consciousness.

Diagnosing Hypoglycemia:

Hypoglycemia is diagnosed by measuring blood sugar levels using a glucose meter. A blood sugar level below 70 mg/dL is generally considered hypoglycemia.

  • Self-Monitoring: The most common method involves checking blood sugar levels with a glucose meter when symptoms arise.
  • Continuous Glucose Monitoring (CGM): CGMs provide real-time blood sugar readings and can alert users to impending lows.
  • Medical Evaluation: If hypoglycemia is recurring or severe, a doctor may conduct further tests to identify the underlying cause.

Managing Hypoglycemia:

The primary goal of treating hypoglycemia is to raise blood sugar levels quickly.

  • The 15-15 Rule: If you experience symptoms of hypoglycemia and your blood sugar is below 70 mg/dL, eat or drink 15 grams of fast-acting carbohydrates (such as glucose tablets, fruit juice, or regular soda). Wait 15 minutes, then check your blood sugar again. If it's still below 70 mg/dL, repeat the process until your blood sugar is within a safe range.
  • Glucagon Injection: For severe hypoglycemia (such as when someone is unconscious), a glucagon injection can be administered to raise blood sugar levels quickly. Glucagon is a hormone that stimulates the liver to release stored glucose into the bloodstream. Family members or caregivers of people at risk for severe hypoglycemia should be trained on how to administer glucagon.
  • Medical Identification: Wear a medical identification bracelet or carry a medical ID card that indicates you have diabetes and are at risk for hypoglycemia. This will alert emergency responders to your condition if you are unable to communicate.
  • Regular Monitoring: Consistently monitor blood glucose levels, especially before meals, before bed, and after exercise. This will help prevent hypoglycemic episodes and assist with medication and dietary adjustments.

| Type of Carbohydrate | Grams of Carbohydrate | Effect on Blood Sugar | | :------------------------ | :-------------------- | :---------------------- | | Glucose Tablets | 15 grams | Rapid increase | | Fruit Juice (4 ounces) | 15 grams | Rapid increase | | Regular Soda (4 ounces) | 15 grams | Rapid increase | | Hard Candy (3-4 pieces) | 15 grams | Moderate increase | | Honey (1 tablespoon) | 17 grams | Rapid increase |

Prevention Strategies for Both Conditions

Related reading: Common Factors Affecting Blood Sugar That Might Surprise You

Prevention is key in managing both hyperglycemia and hypoglycemia.

For Hyperglycemia:

  • Adhere to your diabetes management plan: This includes taking medications as prescribed, following a healthy diet, and exercising regularly.
  • Monitor your blood sugar regularly: This will help you identify patterns and make adjustments to your treatment plan as needed.
  • Eat balanced meals: Focus on whole foods, lean proteins, healthy fats, and high-fiber carbohydrates.
  • Stay hydrated: Drink plenty of water to help your kidneys flush out excess glucose.
  • Manage stress: Practice stress-reduction techniques such as yoga, meditation, or deep breathing exercises.

For Hypoglycemia:

  • Take medications as prescribed: Be careful not to take too much insulin or diabetes medication.
  • Eat regular meals and snacks: Avoid skipping meals or eating too little.
  • Adjust medication or food intake for exercise: If you exercise more than usual, you may need to reduce your insulin dose or eat extra carbohydrates.
  • Be cautious with alcohol: Drink alcohol in moderation and always with food.
  • Educate yourself and your loved ones: Learn the symptoms of hypoglycemia and how to treat it. Teach family members and friends how to administer glucagon in case of a severe episode.
  • Continuous Glucose Monitoring (CGM): Real-time monitoring assists in proactive blood sugar management. CGMs are beneficial, particularly in individuals prone to frequent or severe hypoglycemic episodes.

When to Seek Medical Attention

It's important to know when to seek medical attention for hyperglycemia and hypoglycemia.

Seek immediate medical attention for Hyperglycemia if:

Related reading: Your A1C Blood Sugar Goal How To Understand It And How To Reach It

  • You have symptoms of diabetic ketoacidosis (DKA), such as nausea, vomiting, abdominal pain, fruity-smelling breath, and rapid, deep breathing.
  • Your blood sugar is consistently above 300 mg/dL despite taking steps to lower it.
  • You are unable to keep fluids down due to nausea or vomiting.

Seek immediate medical attention for Hypoglycemia if:

  • You are experiencing severe symptoms such as seizures or loss of consciousness.
  • You are unable to treat the hypoglycemia yourself.
  • You have frequent episodes of hypoglycemia.

Understanding the differences between hyperglycemia and hypoglycemia, recognizing their warning signs, and knowing how to manage them are critical for maintaining good health, especially if you have diabetes. By following these guidelines and working closely with your healthcare team, you can effectively manage your blood sugar levels and reduce your risk of complications. Always consult with your doctor or a diabetes educator for personalized advice and treatment.