Study: High Doses Of Saccharin Don't Lead To Diabetes In Healthy Adults | Ohio State Medical Center [bf425d]

2025-07-18

Post Time: 2025-07-18

Postprandial blood sugar, also known as after-meal blood sugar, refers to the glucose levels in your blood two hours after eating a meal. Understanding postprandial blood sugar is crucial for managing overall health, particularly for individuals with diabetes or those at risk of developing it. Monitoring these levels can help you understand how your body responds to different types of food, allowing you to make more informed dietary choices. This article provides a concise guide on what postprandial blood sugar is, why it matters, and how to manage it effectively.

The process of postprandial blood sugar involves the body’s digestion of carbohydrates, which are broken down into glucose. This glucose enters the bloodstream, causing blood sugar levels to rise. Insulin, a hormone produced by the pancreas, then helps transport glucose from the blood into cells, where it can be used for energy. When this process works effectively, blood sugar levels return to normal within a couple of hours after eating. However, disruptions to this system, such as insulin resistance or deficiency, can lead to elevated postprandial blood sugar levels. Ignoring these spikes can lead to long-term health complications, making regular monitoring an essential practice.


Understanding Postprandial Glucose Levels: Normal vs. Abnormal

Understanding the difference between normal and abnormal postprandial blood sugar levels is critical for maintaining health. The following table provides a general guideline for postprandial blood sugar targets for adults:

Category Postprandial (2 Hours After Meal) Blood Sugar Level (mg/dL)
Normal Less than 140
Prediabetes 140 - 199
Diabetes 200 or higher

These figures are typically used for non-pregnant adults. For those managing their blood glucose more closely due to diagnosed conditions like diabetes, the target might be individualized according to advice from a healthcare professional. In addition to these values, glycosylated hemoglobin (HbA1c) test, a measure of long-term glucose control over the past two to three months, is a vital aspect for healthcare providers in identifying individuals at risk of diabetes or monitor the effectiveness of a treatment plan. While it's good practice to monitor both postprandial and fasting blood glucose, the postprandial blood glucose test gives vital insight into how the body responds to food consumed.

Elevated postprandial blood sugar levels (hyperglycemia) can occur due to various reasons, including:

  • Dietary choices: Consuming meals high in carbohydrates and sugars can lead to significant spikes.
  • Insufficient insulin production or action: In individuals with diabetes, the body either doesn't produce enough insulin or can't use it effectively.
  • Lack of physical activity: Exercise helps improve insulin sensitivity and glucose uptake by cells.

On the other hand, lower than normal levels (hypoglycemia) after eating can occur, although this is less common than hyperglycemia after eating. The most common cause is Reactive Hypoglycemia, and more research is underway to ascertain specific reasons why this occurs in individuals, although it can usually be managed with dietary modifications.


Factors Influencing Postprandial Blood Sugar Spikes

Several factors influence how high your blood sugar spikes after a meal. Understanding these can help you better manage your postprandial glucose levels.

  1. Type and amount of carbohydrates: The glycemic index (GI) and glycemic load (GL) of foods are crucial. High-GI foods, such as white bread, sugary drinks, and pastries, cause rapid spikes in blood sugar. Low-GI foods like whole grains, legumes, and most non-starchy vegetables, result in a more gradual increase. The quantity of carbohydrates also plays a crucial role. Larger portions will usually cause a more significant rise in glucose.

    Example: Eating a bowl of white pasta (high GI) will likely result in a quicker and higher blood sugar spike compared to a bowl of brown rice (lower GI) of the same serving size.

  2. Fiber content: Foods rich in fiber, such as vegetables, fruits, and whole grains, slow down the absorption of sugar into the bloodstream.

    Example: An apple with its skin will cause a slower blood sugar increase compared to apple juice which has lost the fibre.

  3. Fat and protein content: Including fats and proteins in your meals can help slow down carbohydrate digestion and absorption, mitigating rapid blood sugar spikes.

    Example: Combining chicken breast with brown rice and steamed broccoli has a much better impact on blood sugar control than a simple serving of white rice alone.

  4. Meal timing: Eating meals irregularly can also affect blood sugar control. It is better to eat meals within regular periods. Studies show that eating late meals at night can have adverse effects on blood sugar control.

  5. Physical Activity: Physical activities play a critical role in blood glucose regulation, increasing insulin sensitivity and improving uptake. If physical activity is scheduled within 1-2 hours after a meal, that can improve postprandial blood glucose values. However, there is a consideration as it may also contribute to episodes of reactive hypoglycemia. For this reason, it's advisable to consult a healthcare practitioner for personalized advice.

  6. Stress and illness: Both physical and emotional stress can influence blood sugar levels. Illness can also disrupt normal blood sugar regulation.

    Example: The stress associated with a major event or chronic sleep deprivation can cause spikes in glucose, while dealing with illnesses such as the flu can also destabilize glycemic control.


Practical Tips for Managing Postprandial Blood Sugar

Managing postprandial blood sugar effectively involves making sustainable lifestyle adjustments. Here are some practical steps to help control your blood glucose levels:

  1. Choose low-GI foods: As explained above, selecting low glycemic index (GI) and glycemic load (GL) foods can help with better blood glucose control. Be sure to focus on healthy foods like lean meats, non-starchy vegetables, whole grains, and healthy fats. It's worth noting that while a particular food is ranked lower GI, it does not automatically make it healthier; therefore, one should focus on a healthy well-balanced diet.

    Example: Swap sugary cereals for oatmeal, white bread for whole-grain, and white potatoes for sweet potatoes.

  2. Portion control: Eating too much at once can lead to a significant blood sugar spike, even if you choose healthier food items. Consider using smaller plates and measuring food portions when appropriate to avoid overeating.

    Example: Instead of a big portion of white rice, have half the size and add extra green leafy vegetables instead.

  3. Pair carbohydrates with protein and healthy fats: By adding proteins and fats, this helps slow down carbohydrate digestion and glucose absorption.

    Example: Pair an apple with a handful of almonds or use nut butter.

  4. Time meals appropriately: As mentioned earlier, regular eating schedules are important. Avoid long gaps between meals and be consistent. Consider consuming smaller meals and avoiding large portions in any single meal.

  5. Increase fiber intake: Add more high-fiber food items, such as vegetables, fruits, legumes, and whole grains. Dietary fibre reduces postprandial spikes by delaying absorption.

    Example: Include leafy greens or beans in your meals. Snack on an apple instead of juice.

  6. Engage in regular physical activity: Physical exercise helps to increase insulin sensitivity, thereby lowering blood glucose levels. Try to incorporate exercise regularly into your daily or weekly schedule.

    Example: Walking for 20 minutes after a meal can improve your glucose level.

  7. Monitor blood sugar levels: Regular checks of blood sugar levels with a glucose meter at home can provide a clear picture of how different meals affect glucose, especially if you have diabetes. It helps with understanding what kind of foods might be detrimental for your blood glucose and you can alter your diet accordingly.

  8. Seek professional guidance: Consult a healthcare provider or a registered dietitian for personalized advice.

By implementing these strategies, individuals can better manage their postprandial blood sugar levels, reducing the risk of long-term health complications and improving overall well-being.

Learn more: (COLUMBUS, Ohio) – For those trying to live a healthy lifestyle, the choice between sugar and artificial sweeteners can be confusing. A new study by researchers at The Ohio State medicare blood sugar monitor University Wexner Medical Center offers some clarity on the safety of artificial sweeteners like saccharin for healthy adults. The study found the sugar substitute saccharin doesn’t lead to diabetes in healthy adults as previous studies have suggested. The study findings are published in the journal Microbiome ( “It’s not that the findings of previous studies are wrong, they just didn’t control for things like underlying health conditions, diet choices and lifestyle habits,” said George Kyriazis, PhD, assistant professor of biological chemistry and pharmacology at Ohio State and co-author of the study. “By studying the artificial sweetener saccharin in healthy adults, 84 blood sugar we have isolated its effects and found no change in participants’ gut microbiome or their metabolic profiles.” In the study, healthy participants were given the maximum recommended amount of saccharin every day for two weeks, which is far more than the average consumer would use. They also tested the effects of saccharin in mice with the same results: the artificial sweetener did not cause any biological changes or cause any adverse health effects. “Sugar, on the other hand, is well-documented to contribute to obesity, heart disease and diabetes,” Kyriazis said. “So when given the choice, artificial sweeteners like saccharin are the clear winner based on all the scientific information we lowering blood sugar levels currently have.” Future research will study each FDA-approved sweetener individually to examine if there are any differences in how they are metabolized. Researchers will also look at these substances over a longer period of time to ensure they are safe for those who use them in their daily lives.
Study: High doses of saccharin don't lead to diabetes in healthy adults | Ohio State Medical Center
Study: High Doses Of Saccharin Don't Lead To Diabetes In Healthy Adults | Ohio State Medical Center [bf425d]