Novel Water-Solubilized CBD-based Sublingual Tablets Treat Diabetic Neuropathic Pain - Debra Kimless [365d22]
Novel Water-Solubilized CBD-based Sublingual Tablets Treat Diabetic Neuropathic Pain - Debra Kimless [365d22]
2025-07-18
Post Time: 2025-07-18
## Unlocking the Science of Serenity: The Role of CBD in Wellness The use of cannabidiol (CBD) gummies for stress relief, sleep enhancement, and hair health is grounded in promising scientific research. Studies indicate that CBD interacts with receptors in our brain's endocannabinoid system—a complex network involved in regulating mood, sleep patterns, and physiological processes like inflammation. This interaction may result in reduced anxiety levels and improved sleep quality by promoting the release of calming neurotransmitters such as serotonin. Furthermore, some researchers propose that this same mechanism could support hair health by reducing stress-induced hormonal imbalances known to exacerbate conditions like telogen effluvium—a temporary form of hair thinning linked to severe stress. While more specific studies are needed in the context of CBD and hair care, existing evidence supports its potential role as a holistic remedy for multiple wellness concerns. ## Navigating the Path: The Endocannabinoid System's Influence CBD gummies find their efficacy through interaction with our body’s endocannabinoid system (ECS), which is integral to maintaining homeostasis. This complex system plays a crucial part in regulating various bodily functions, including mood stabilization and sleep-wake cycles. When consumed, CBD may enhance the ECS by mimicking naturally occurring cannabinoids or inhibiting their breakdown—leading to increased availability of these calming compounds. This process promotes relaxation without significant side effects often associated with traditional pharmaceuticals, making CBD gummies a compelling option for those seeking natural wellness solutions. ## Beyond Pills: Comparing Relief Options When managing anxiety and sleep disorders, individuals often face the decision between using traditional medications or exploring alternative treatments like CBD gummies. Pharmaceutical drugs can be effective but may come with drawbacks such as potential dependency issues, side effects (drowsiness, dizziness), and withdrawal symptoms upon cessation. Conversely, CBD gummies offer a natural alternative perceived by many to have fewer adverse effects. However, it's important to consider dosage accuracy—since edibles take longer to metabolize—and legal status in certain areas or age groups. Both options require consultation with healthcare providers for safe usage tailored to individual health needs and conditions. ## The Wellness Journey: Combining CBD Gummies with Lifestyle Practices For a comprehensive approach to managing stress, insomnia, and hair thinning, incorporating CBD gummies into an overall wellness routine can be highly effective. These gummies can synergize well with practices like meditation, yoga, or aromatherapy—each known for promoting relaxation and mental clarity. Meditation helps cultivate mindfulness by training the mind to focus on present sensations rather than stressors of daily life. When combined with CBD's calming properties, it creates a powerful tool against anxiety and insomnia. Yoga offers physical movement along with breathing techniques that can further enhance one’s state of calmness and sleep readiness when used alongside CBD gummies. ## Empowering Your Choices: Selecting the Right Product When choosing a CBD gummy product to incorporate into your wellness plan, several factors must be considered for optimal benefits. Prioritize products from reputable companies that provide clear information about potency—measured in milligrams of CBD per serving—and include full-spectrum extracts rather than isolates to take advantage of other beneficial cannabinoids present. Additionally, scrutinize the ingredient list for natural sweeteners and preservatives while verifying third-party lab testing reports ensuring product purity and safety. Educating oneself on these aspects ensures a healthier relationship with any CBD gummies chosen as part of one's stress or sleep management regimen. ## Beyond Misconceptions: Demystifying CBD Many people harbor misconceptions about the nature and effects of cannabidiol (CBD), which can influence its perception and usage effectiveness. Common myths include concerns over legality, safety, addiction potential, and psychoactive properties—which primarily concern THC rather than CBD itself. CBD is legal in many places at a federal level but may be restricted depending on local laws or specific use cases like edibles for minors. Contrary to addictive substances that alter brain chemistry significantly leading to dependence, scientific studies generally support the safety of CBD when consumed responsibly and in recommended doses. These clarifications help potential users approach CBD gummies with accurate information—maximizing their stress management benefits while minimizing fears based on misinformation. By understanding these facets—from science backing its use for anxiety relief through holistic lifestyle integration—you are better equipped to explore how CBD can complement your journey toward improved mental wellness and physical health.Tags: Diabetic Peripheral Neuropathy Treatment, DPN, PEA, CBD, Palmitoylethanolamide, Clinical Trial, Cannabis Research Studies, Medicine Debra Kimless, MD, presents, "Novel Water-Solubilized CBD-based Sublingual Tablets Treat Diabetic Neuropathic Pain" at CannMed 23. 0:00 Intro 0:12 Disclosures 0:46 CannMed Conference 3:00 Sublingual CBD/PEA for the Treatment of Painful Diabetic Peripheral Neuropathy (DPN) of the Feet 3:58 Current Rx 4:18 Cannabidiol & Palmitoylethanolamide 4:57 Steps to Improve Bioavailability 5:40 Trial Participants 6:12 Pain Response 7:10 be happy gummy cbd Anxiety Response 7:32 Sleep Response 8:07 Randomized, Double-Blind Placebo-Controlled Trial 8:23 Endpoints 8:33 Participants 9:06 Treatments 9:24 Pain Response 11:35 Anxiety 12:05 Sleep 12:18 Patient Global Impression of Change 12:45 Safety 13:12 Summary 15:00 Q&A Prove the hypothesis that the water-solubilized CBD tablets were an effective treatment for Diabetic Neuropathic Pain (pDPN) and submit an IND to the FDA for approval of this novel pain relief therapy. Conducting first a proof-of-concept open label trial (21 days) and then a double blind, placebo controlled randomized trial (28 days) can you take cbd gummy and drink alcohol using water-solubilized CBD sublingual tablets for the treatment of diabetic neuropathic pain of the feet (pDPN). Both clinical trials were conducted remotely using a web-based platform. The participants thera bloom cbd gummies completed the trials without leaving their homes. This novel approach was developed and initiated prior to the onset of the pandemic and continued uninterrupted. The goals for both studies were safety, and efficacy of the tablets for the treatment of pDPN, poor sleep, and anxiety, and to assess the patient’s global impression of change (PGIC). Participants who received active drug were taking water solubilized 20mg CBD sublingually three times a day. Learn More about CannMed: